170 Results for "

Euphorbia milii Des Moul.

" in MedChemExpress (MCE) Product Catalog:
Products (170)

170 Results for "Euphorbia milii Des Moul." in MCE Product Catalog:

13
13 Publications Verification
Cat. No.: HY-N2333
CAS No.: 57444-62-9
Synonyms: (+)-Resiniferatoxin
Resiniferatoxin ((+)-Resiniferatoxin), is a selective agonist of transient receptor potential vanilloid 1 (TRPV1) receptor agonist. Resiniferatoxin can be isolated from the Euphorbia resinifera plant. Resiniferatoxin eliminates TRPV1+ primary sensory afferents and blunt cardiac sympathetic afferent reflex for a relatively long period .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-N0866
CAS No.: 54706-99-9
20-Deoxyingenol, a diterpene, is isolated from the roots of Euphorbia kansui. 20-Deoxyingenol can promote autophagy and lysosomal biogenesis by promoting the nuclear translocation of transcription factor EB (TFEB) in vitro. 20-Deoxyingenol can be used for the research of osteoarthritis (OA) .
loading...
    loading...
5
5 Cited Publications
Cat. No.: HY-B0719
CAS No.: 75567-37-2
Synonyms: Ingenol 3-angelate; PEP005
Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-14598
CAS No.: 56-53-1
Purity:  99.62%
Diethylstilbestrol is a non-steroidal female hormone that has oral activity and can act on menopausal and postmenopausal disorders. Diethylstilbestrol can induce DNA oxidation and Apoptosis of spermatogonial stem cells. Diethylstilbestrol can induce thymocyte Autophagy Diethylstilbestrol is a 11β-hydroxysteroid dehydrogenase 2 (HSD11B2) inhibitor. .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P0298A
CAS No.: 23827-91-0
[Des-Arg9]-Bradykinin acetate is a Bradykinin B1 receptor agonist that displays selectivity for B1 over B2 receptors.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P1366
CAS No.: 293735-04-3
Target:  

GHSR

Research Areas:  

Metabolic Disease

des-Gln14-Ghrelin is a second endogenous ligand for the growth hormone secretagogue receptor. a). des-Gln14-ghrelin potently induces increases in [Ca 2+]i in CHO-GHSR62 cells, with an EC50 of 2.4 nM .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P0048
CAS No.: 52435-06-0
Synonyms: Surfagon
Target:  

GnRH Receptor

Research Areas:  

Others

(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N9542
CAS No.: 53798-97-3
Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N0732
CAS No.: 37905-08-1
Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud with oral activity. Jolkinolide B downregulates XIAP, cIAP1, cIAP2, and phosphorylated Akt, upregulates Smac, activates caspase-3 and caspase-9, and inhibits NF-κB, TGFβ/smad3 and JAK/STAT3 pathways. Jolkinolide B exerts comprehensive biological effects including inducing cancer cell apoptosis, suppressing inflammatory responses, improving lung function, alleviating hepatic steatosis and eliminating intracellular Mycobacterium tuberculosis. Jolkinolide B can be used for the research of leukemia, histiocytic lymphoma, asthma, metabolic dysfunction-associated steatotic liver disease and tuberculosis .
loading...
    loading...
Cat. No.: HY-P1526
CAS No.: 111863-73-1
ANP [Des18-22] 4-23 amide rat is a polypeptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds NPR-C .
loading...
    loading...
Cat. No.: HY-N5001
CAS No.: 218916-51-9
Euphorbia factor L2, a lathyrane diterpenoid isolated from caper euphorbia seed (the seeds of Euphorbia lathyris L.), has been traditionally applied to treat cancer. Euphorbia factor L2 shows potent cytotoxicity and induces apoptosis via a mitochondrial pathway .
loading...
    loading...
Cat. No.: HY-P4463
CAS No.: 38280-53-4
Target:  

GnRH Receptor

Research Areas:  

Others

(Des-Pyr1)-LHRH is a Polypeptide Internal Standard, identical to (Des-Pyr1)-GnRH, which can be identified through peptide screening. Peptide screening is a research tool that mainly collects active polypeptides via immunoassays. It can be applied to protein interaction, functional analysis, epitope screening, especially in the field of active molecule research and development. (Des-Pyr1)-LHRH can serve as an internal standard (ISTD) for mass spectrometry analysis .
loading...
    loading...
Cat. No.: HY-N2556
CAS No.: 514-46-5
Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages .
loading...
    loading...
Cat. No.: HY-P4676
CAS No.: 71800-37-8
Target:  

Bradykinin Receptor

Research Areas:  

Inflammation/Immunology

Lys-(Des-Arg9,Leu8)-Bradykinin is a selective bradykinin B1 receptor (BDKRB1) antagonist. Lys-(Des-Arg9,Leu8)-Bradykinin inhibits local inflammatory edema. Lys-(Des-Arg9,Leu8)-Bradykinin induces the production of systemic acute-phase proteins. Lys-(Des-Arg9,Leu8)-Bradykinin is applicable to research related to peptidoglycan-polysaccharide-induced acute arthritis .
loading...
    loading...
Cat. No.: HY-P1143A
Target:  

GCGR

Research Areas:  

Metabolic Disease

[Des-His1,Glu9]-Glucagon amide TFA is a potent and peptide antagonist of the glucagon receptor, with a pA2 of 7.2. [Des-His1,Glu9]-Glucagon amide TFA is potentially useful in the study of the pathogenesis of diabetes .
loading...
    loading...
Cat. No.: HY-103291
CAS No.: 126959-88-4
Purity:  99.96%
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .
loading...
    loading...
Cat. No.: HY-P4409
CAS No.: 290312-22-0
Target:  

Peptides

Research Areas:  

Others

(Des-Ala3)-GHRP-2 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
loading...
    loading...
Cat. No.: HY-137242
CAS No.: 52557-26-3
Purity:  99.65%
Ingenol-3-palmitate, an ingenane diterpenoid, is a nature product that could be isolated from the roots of Euphorbia ebracteolata. Ingenol-3-palmitate is a potent HIV-1 (HIV) inhibitor with an IC50 value of 4.1 nM .
loading...
    loading...
Cat. No.: HY-P1143
CAS No.: 110084-95-2
Target:  

GCGR

Research Areas:  

Metabolic Disease

[Des-His1,Glu9]-Glucagon amide is a potent and peptide antagonist of the glucagon receptor, with a pA2 of 7.2. [Des-His1,Glu9]-Glucagon amide is potentially useful in the study of the pathogenesis of diabetes .
loading...
    loading...
Cat. No.: HY-N12730
CAS No.: 81557-52-0
Euphoscopin B (compound 5) is a cytotoxic macrocyclic diterpene isolated from Euphorbia helioscopia L .
loading...
    loading...